Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591501 | 0.86 | LMNA (0.48) | LMNAMEN1KMT2APRPS1FGFR1 | |
| SCHEMBL2268683 | 0.84 | LMNA (0.51) | LMNAMEN1KMT2APRPS1FGFR1 | |
| SCHEMBL9598443 | 0.83 | MEN1 (0.49) | LMNAMEN1KMT2APRPS1FGFR1 | |
| SCHEMBL9569986 | 0.83 | MEN1 (0.49) | LMNAMEN1KMT2APRPS1FGFR1 | |
| SCHEMBL2273596 | 0.80 | FGFR1 (0.51) | LMNAMEN1KMT2APRPS1FGFR1 | |
| SCHEMBL4873272 | 0.80 | HDAC6 (0.68) | KMT2ATNFHDAC6ALDH1A1HDAC3 | |
| SCHEMBL9040429 | 0.79 | MTNR1A (0.61) | LMNAMEN1KMT2AFGFR1MAPT | |
| SCHEMBL9041325 | 0.79 | MAPT (0.51) | LMNAMEN1KMT2AFGFR1MAPT | |
| SCHEMBL9037446 | 0.79 | LMNA (0.76) | LMNAMEN1KMT2AMAPTTP53 | |
| SCHEMBL9040262 | 0.77 | PRPS1 (0.52) | LMNAMEN1KMT2APRPS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393574-B1 | Hexitol derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5053408-A | Cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0393574-A2 | Hexitol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |