Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570225 | 1.00 | AGTR1 (0.41) | AGTR1AGTR2TP53RAB9APPARG | |
| SCHEMBL9570094 | 0.89 | ACHE (0.37) | AGTR1AGTR2TP53RAB9APPARG | |
| SCHEMBL9570085 | 0.85 | PPARG (0.44) | AGTR1AGTR2TP53RAB9APPARG | |
| SCHEMBL9570070 | 0.85 | PPARG (0.44) | AGTR1AGTR2TP53RAB9APPARG | |
| SCHEMBL9570077 | 0.85 | PPARG (0.37) | AGTR1PPARG | |
| SCHEMBL9570069 | 0.85 | PPARG (0.37) | AGTR1PPARG | |
| SCHEMBL9570160 | 0.78 | AGTR1 (0.47) | AGTR1AGTR2TP53RAB9APPARG | |
| SCHEMBL9570136 | 0.77 | PPARG (0.38) | AGTR1PPARG | |
| SCHEMBL9570198 | 0.77 | AGTR1 (0.39) | AGTR1PPARG | |
| SCHEMBL9570192 | 0.77 | AGTR1 (0.39) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |