Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570018 | 0.93 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNACA12CA9 | |
| SCHEMBL3310896 | 0.88 | ALDH1A1 (0.64) | ALDH1A1HPGDLMNACA12CA9 | |
| SCHEMBL19404635 | 0.88 | ALDH1A1 (0.64) | ALDH1A1HPGDLMNACA12CA9 | |
| SCHEMBL11770064 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNACA12CA9 | |
| SCHEMBL8880040 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNACA12CA9 | |
| SCHEMBL9692960 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNACA12CA9 | |
| SCHEMBL2477201 | 0.84 | ALDH1A1 (0.59) | ALDH1A1HPGDLMNATSHRTDP1 | |
| SCHEMBL9432738 | 0.83 | MMP1 (0.48) | ALDH1A1HPGDLMNACA12CA9 | |
| SCHEMBL9631729 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HPGDLMNATSHRTDP1 | |
| SCHEMBL782029 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HPGDLMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |