Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598513 | 0.82 | PDE10A (0.46) | PDE10AHRH3KDM4EALDH1A1POLB | |
| SCHEMBL23530802 | 0.82 | PDE10A (0.46) | PDE10AHRH3KDM4EALDH1A1POLB | |
| SCHEMBL13384210 | 0.82 | PDE10A (0.46) | PDE10AHRH3KDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL28842920 | 0.81 | PDE10A (0.45) | PDE10AHRH3KDM4EALDH1A1POLB | |
| SCHEMBL9570471 | 0.75 | MAPT (0.55) | PDE10AKDM4EALDH1A1POLBTDP1 | |
| SCHEMBL13403196 | 0.75 | KDM4E (0.43) | PDE10AHRH3KDM4EALDH1A1POLB | |
| SCHEMBL23530698 | 0.74 | PDE10A (0.41) | PDE10AHRH3KDM4EALDH1A1RAB9A | |
| SCHEMBL4891633 | 0.71 | HRH3 (0.36) | PDE10AHRH3KDM4EALDH1A1KMT2A | |
| SCHEMBL20758571 | 0.71 | HPGD (0.52) | PDE10AKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL9570185 | 0.70 | KDM4E (0.68) | KDM4EALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |