Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035766 | 0.75 | — | — | |
| SCHEMBL870663 | 0.75 | GAA (0.48) | HRH3PDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL13403196 | 0.75 | KDM4E (0.43) | HRH3PDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL9570309 | 0.71 | PDE10A (0.46) | HRH3PDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL28842799 | 0.70 | GAA (0.40) | HRH3PDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL4885799 | 0.70 | SMN1; SMN2 (0.53) | KDM4EALDH1A1KMT2A | |
| SCHEMBL28842805 | 0.69 | NOS3 (0.42) | HRH3PDE10AKDM4EALDH1A1 | |
| SCHEMBL23530802 | 0.68 | PDE10A (0.46) | HRH3PDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL13384210 | 0.68 | PDE10A (0.46) | HRH3PDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL10974012 | 0.67 | NOS2 (0.43) | KDM4EALDH1A1KMT2ATERTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171740-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-17 | — | — | US | disclosed |
| EP-1793825-A2 | CHEMCIAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006036816-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171740-A1 | Chemical Compounds | CXCR4, CCR5, CXCR3 | HRH3 816/4885PDE10A 2629/4885KDM4E 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.