Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796383 | 0.79 | NPC1 (0.37) | KDM4EALDH1A1RAB9ANPC1PIK3CG | |
| SCHEMBL16376291 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28842805 | 0.76 | NOS3 (0.42) | KDM4EALDH1A1HRH3PDE10ANOS3 | |
| SCHEMBL26032200 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL23530802 | 0.75 | PDE10A (0.46) | KDM4EALDH1A1HRH3PDE10AKMT2A | |
| SCHEMBL4891633 | 0.75 | HRH3 (0.36) | KDM4EALDH1A1HRH3PDE10AKMT2A | |
| SCHEMBL9570309 | 0.75 | PDE10A (0.46) | KDM4EALDH1A1HRH3PDE10AKMT2A | |
| SCHEMBL13384210 | 0.75 | PDE10A (0.46) | KDM4EALDH1A1HRH3PDE10AKMT2A | |
| SCHEMBL9598513 | 0.75 | PDE10A (0.46) | KDM4EALDH1A1HRH3PDE10AKMT2A | |
| SCHEMBL28842799 | 0.74 | GAA (0.40) | KDM4EALDH1A1HRH3PDE10AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696210-B2 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2010-04-13 | — | — | US | disclosed |