Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | FAAH | O00519 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96977 | 0.93 | MEN1 (0.63) | MEN1KMT2AFAAHMAPK1EPHX2 | |
| SCHEMBL12934925 | 0.91 | FAAH (0.78) | MEN1KMT2AFAAHMAPK1EPHX2 | |
| SCHEMBL12934924 | 0.88 | FAAH (0.83) | MEN1KMT2AFAAHMAPK1EPHX2 | |
| SCHEMBL12934928 | 0.88 | FAAH (0.83) | MEN1KMT2AFAAHMAPK1EPHX2 | |
| SCHEMBL12934930 | 0.88 | FAAH (0.83) | MEN1KMT2AFAAHMAPK1EPHX2 | |
| SCHEMBL5909190 | 0.85 | FAAH (0.71) | MEN1KMT2AFAAHMAPK1EPHX2 | |
| SCHEMBL16488593 | 0.83 | — | — | |
| SCHEMBL9570401 | 0.82 | FAAH (0.67) | MEN1KMT2AFAAHMAPK1EPHX2 | |
| SCHEMBL12333288 | 0.82 | FAAH (0.67) | MEN1KMT2AFAAHMAPK1EPHX2 | |
| SCHEMBL5737558 | 0.82 | FAAH (0.96) | MEN1KMT2AFAAHMAPK1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |