Sugi Predict

Sugi Predict / Compounds / SCHEMBL5737558

SCHEMBL5737558

SCHEMBL5737558

CCCCCC(=O)NC(C)C

nearest known ligand 0.96

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 5/20 0.96
▸ MEN1 O00255 2/20 0.96
▸ KMT2A Q03164 2/20 0.96
▸ MAPK1 P28482 1/20 0.96
▸ DNM1 Q05193 1/20 0.58
▸ HSP90AA1 P07900 1/20 0.56
▸ NOD1 Q9Y239 1/20 0.53
▸ PLA2G2C Q5R387 1/20 0.53
▸ PLA2G10 O15496 2/20 0.53
▸ EPHX1 P07099 1/20 0.52
▸ ASAH2 Q9NR71 1/20 0.51
▸ ALDH1A1 P00352 1/20 0.50
▸ ASAH1 Q13510 1/20 0.50
▸ ACER2 Q5QJU3 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1456458 0.98 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL1456455 0.98 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL12377250 0.98 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
Hexadecanoic Acid Isopropylamide SCHEMBL1457147 0.98 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL20143550 0.98 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL277126 0.98 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL4023787 0.98 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL1456463 0.98 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL12459875 0.98 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL19557778 0.98 FAAH (1.00) FAAHMEN1KMT2AMAPK1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543936-A4 RENIN INHIBITORS — 1993-06-30 — — EP claimed
EP-0543936-A1 RENIN INHIBITORS ABBOTT LABORATORIES (US) 1993-06-02 — — EP claimed
WO-1992003429-A1 RENIN INHIBITORS ABBOTT LABORATORIES (US) 1992-03-05 — — WO claimed
EP-0437508-A4 NON-PEPTIDE RENIN INHIBITORS — 1991-11-06 — — EP claimed
EP-0437508-A1 NON-PEPTIDE RENIN INHIBITORS ABBOTT LABORATORIES (US) 1991-07-24 — — EP claimed
WO-1990003971-A1 NON-PEPTIDE RENIN INHIBITORS ABBOTT LABORATORIES (US) 1990-04-19 — — WO claimed
US-20230158169-A1 LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE AUDAX PRIVATE DEBT LLC, AS AGENT 2023-05-25 — — US disclosed
US-11008325-B2 Inhibitors of cancer invasion, attachment, and/or metastasis VIRGINIA COMMONWEALTH UNIVERSITY (US) 2021-05-18 — — US disclosed
US-10993983-B2 Cyclic peptide epitopes and small-molecule mimics for inducing autophagy TRUSTEES OF TUFTS COLLEGE (US) 2021-05-04 — — US disclosed
US-10683387-B2 Bottlebrush copolymers and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-06-16 — — US disclosed
US-20190263824-A1 INHIBITORS OF CANCER INVASION, ATTACHMENT, AND/OR METASTASIS VIRGINIA COMMONWEALTH UNIVERSITY 2019-08-29 — — US disclosed
WO-2019164977-A1 FLUORINATED NUCLEOTIDES AND USES THEREOF Singular Genomics Systems, Inc. (US) 2019-08-29 — — WO disclosed
US-20180094099-A1 BOTTLEBRUSH COPOLYMERS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-04-05 — — US disclosed
EP-0444156-A1 METHOD FOR TREATING VASCULAR DISEASES ABBOTT LABORATORIES (US) 1991-09-04 — — EP disclosed
EP-0439556-A1 HETEROCYCLIC PEPTIDE RENIN INHIBITORS ABBOTT LABORATORIES (US) 1991-08-07 — — EP disclosed
EP-0437508-A1 NON-PEPTIDE RENIN INHIBITORS ABBOTT LABORATORIES (US) 1991-07-24 — — EP disclosed
WO-1990005531-A1 METHOD FOR TREATING VASCULAR DISEASES ABBOTT LABORATORIES (US) 1990-05-31 — — WO disclosed
WO-1990004917-A1 HETEROCYCLIC PEPTIDE RENIN INHIBITORS ABBOTT LABORATORIES (US) 1990-05-17 — — WO disclosed
WO-1990003971-A1 NON-PEPTIDE RENIN INHIBITORS ABBOTT LABORATORIES (US) 1990-04-19 — — WO disclosed
US-4006182-A Process for the preparation of 1-aminoalkane-1,1-diphosphonic acids HENKEL & CIE G.M.B.H. (DT) 1977-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10993983-B2 Cyclic peptide epitopes and small-molecule mimics for inducing autophagy BECN1, SQSTM1, ATG7 FAAH 4543/4885MEN1 3390/4885KMT2A 4675/4885
US-10683387-B2 Bottlebrush copolymers and uses thereof TRIB1, TRIB2, ABCB11 FAAH 839/4885MEN1 4342/4885KMT2A 4854/4885
US-20190263824-A1 INHIBITORS OF CANCER INVASION, ATTACHMENT, AND/OR METASTASIS SDCBP, SDC1, SDAD1 FAAH 4088/4885MEN1 3338/4885KMT2A 4203/4885
US-20180094099-A1 BOTTLEBRUSH COPOLYMERS AND USES THEREOF TRIB1, TRIB2, ABCB11 FAAH 839/4885MEN1 4342/4885KMT2A 4854/4885
US-20230158169-A1 LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE CTSA, CTSS, CTSV FAAH 645/4885MEN1 3517/4885KMT2A 3207/4885
US-11008325-B2 Inhibitors of cancer invasion, attachment, and/or metastasis SDCBP, SDC1, SDAD1 FAAH 4088/4885MEN1 3338/4885KMT2A 4203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.