Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28945842 | 0.80 | LMNA (0.36) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL25660465 | 0.80 | LMNA (0.32) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| SCHEMBL15538586 | 0.79 | LMNA (0.46) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL17188681 | 0.78 | FFAR3 (0.46) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL3402007 | 0.73 | ALDH1A1 (0.57) | LMNATSHRUSP2ALDH1A1CYP1A2 | |
| SCHEMBL13563890 | 0.73 | ALDH1A1 (0.52) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| SCHEMBL2443279 | 0.72 | LMNA (0.44) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL5903128 | 0.72 | FFAR4 (0.43) | SLC22A6CYP1A2KDM2A | |
| Hydrochloric Acid SCHEMBL2203240 | 0.72 | LMNA (0.33) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL21858440 | 0.72 | TSHR (0.41) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5295238-A | — | — | None | — | — | JP | disclosed |
| JP-H05295238-A | SOLID COMPOSITION OF POLYGLYCIDYL COMPOUND HAVING MOLECULAR WEIGHT OF LESS THAN 1,500 | CIBA GEIGY AG | 1993-11-09 | — | — | JP | disclosed |
| US-4107165-A | ANTICOAGULANTS | ENDO LABORATORIES (US) | 1978-08-15 | — | — | US | disclosed |