Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570558 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8312465 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL1681770 | 0.81 | GAA (0.54) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL1856050 | 0.81 | GAA (0.54) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL3914501 | 0.81 | GAA (0.54) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL7243005 | 0.81 | GAA (0.54) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL3267630 | 0.81 | GAA (0.60) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL249159 | 0.80 | GAA (0.55) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8374769 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL3113016 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |