Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570572 | 1.00 | HTT (0.71) | HTTKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL7356605 | 0.88 | HTT (0.69) | HTTKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL7922185 | 0.86 | HTT (0.68) | HTTKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL11111056 | 0.83 | ALDH1A1 (0.80) | HTTKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL11290866 | 0.82 | HTT (0.71) | HTTKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL11263439 | 0.82 | HTT (0.71) | HTTKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL11263444 | 0.82 | HTT (0.71) | HTTKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL10802880 | 0.81 | ALDH1A1 (0.77) | HTTKMT2AMEN1CYP1A2LMNA | |
| Phenacetin SCHEMBL18894356 | 0.81 | KMT2A (1.00) | HTTKMT2AMEN1CYP1A2LMNA | |
| Phenacetin SCHEMBL23280 | 0.81 | KMT2A (1.00) | HTTKMT2AMEN1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |