Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570695 | 0.87 | ALDH1A1 (0.55) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9570924 | 0.85 | ALDH1A1 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9214159 | 0.83 | ALDH1A1 (0.67) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL8741078 | 0.82 | ALDH1A1 (0.66) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7485715 | 0.82 | KDM4E (0.48) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7978454 | 0.82 | KDM4E (0.48) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6215706 | 0.81 | ALDH1A1 (0.55) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9411089 | 0.81 | ALDH1A1 (0.58) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9411171 | 0.81 | ALDH1A1 (0.58) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9570903 | 0.80 | KCNH2 (0.49) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550903-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1993-07-14 | — | — | EP | disclosed |