SCHEMBL9570729

SCHEMBL9570729

OCC(c1ccc(Br)cc1)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.44
ESR2 Q92731 3/20 0.44
HTR2A P28223 1/20 0.35
CYP1A2 P05177 1/20 0.34
CTSL P07711 2/20 0.34
CTSB P07858 2/20 0.34
CTSS P25774 2/20 0.34
CTSK P43235 2/20 0.34
CYP2A6 P11509 1/20 0.33
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30789013 0.84 ESR1 (0.42) ESR1ESR2HTR2ACYP1A2CTSL
SCHEMBL9570698 0.81 ESR1 (0.46) ESR1ESR2CTSL
SCHEMBL28893969 0.79 ESR1 (0.40) ESR1ESR2HTR2ACYP1A2CTSL
SCHEMBL9560934 0.79 ESR1 (0.44) ESR1ESR2CYP1A2
SCHEMBL9862583 0.79 ESR1 (0.44) ESR1ESR2
SCHEMBL17892089 0.79 CYP1A2 (0.38) HTR2ACYP1A2
SCHEMBL9570823 0.79 ESR1 (0.44) ESR1ESR2
SCHEMBL9570660 0.79 ESR1 (0.44) ESR1ESR2
SCHEMBL9570735 0.79 ESR1 (0.44) ESR1ESR2CTSLCTSBCTSS
SCHEMBL22349242 0.78 ESR1 (0.42) ESR1ESR2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed