SCHEMBL9570698

SCHEMBL9570698

OCC(c1ccc(F)cc1)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
TRPA1 O75762 1/20 0.38
AOC3 Q16853 1/20 0.36
IDO1 P14902 2/20 0.35
TDO2 P48775 2/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
GABBR2 O75899 1/20 0.34
GABBR1 Q9UBS5 1/20 0.34
PLOD2 O00469 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26867066 0.81 TRPA1 (0.46) TRPA1AOC3IDO1TDO2HDAC3
SCHEMBL9570729 0.81 ESR1 (0.44) ESR1ESR2CTSL
SCHEMBL9862583 0.81 ESR1 (0.44) ESR1ESR2
SCHEMBL9570735 0.81 ESR1 (0.44) ESR1ESR2CTSL
SCHEMBL9570660 0.81 ESR1 (0.44) ESR1ESR2
SCHEMBL18022512 0.81 TRPA1 (0.46) TRPA1AOC3IDO1TDO2HDAC3
SCHEMBL9570823 0.81 ESR1 (0.44) ESR1ESR2IDO1
SCHEMBL9560934 0.81 ESR1 (0.44) ESR1ESR2AOC3HDAC4HDAC7
SCHEMBL4122236 0.80 ESR1 (0.42) ESR1ESR2TRPA1
SCHEMBL22349242 0.80 ESR1 (0.42) ESR1ESR2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed