Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570735 | 0.83 | ESR1 (0.44) | ESR1ESR2ALDH1A1 | |
| SCHEMBL9560934 | 0.83 | ESR1 (0.44) | ESR1ESR2SMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL9570590 | 0.81 | PTPN5 (0.43) | ESR1ESR2PTPN5ALDH1A1SMN1; SMN2 | |
| SCHEMBL13966059 | 0.81 | ESR1 (0.41) | ESR1ESR2PTPN5ALDH1A1SMN1; SMN2 | |
| SCHEMBL9570698 | 0.81 | ESR1 (0.46) | ESR1ESR2IDO1 | |
| SCHEMBL14233622 | 0.81 | ESR1 (0.41) | ESR1ESR2PTPN5ALDH1A1SMN1; SMN2 | |
| SCHEMBL9570866 | 0.80 | LMNA (0.44) | ESR1ESR2ALDH1A1SMN1; SMN2TYR | |
| SCHEMBL9570673 | 0.80 | ESR1 (0.50) | ESR1ESR2ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9570755 | 0.80 | ABCB11 (0.46) | ESR1ESR2ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL9570729 | 0.79 | ESR1 (0.44) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545891-A2 | Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4840971-A | INSECTICIDES, MITICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0240978-A2 | Ether compounds, process for their preparation, compositions containing the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-14 | — | — | EP | disclosed |