SCHEMBL9570756

SCHEMBL9570756

CCOc1ccc(C(COCc2cccc(Oc3ccccc3)c2)C(F)(F)F)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CETP P11597 5/20 0.42
FFAR1 O14842 2/20 0.41
MRGPRX4 Q96LA9 4/20 0.39
EGFR P00533 1/20 0.37
PPARD Q03181 2/20 0.36
PPARA Q07869 2/20 0.36
FFAR4 Q5NUL3 1/20 0.36
TACR1 P25103 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570798 0.93 PPARA (0.41) CETPFFAR1MRGPRX4EGFRPPARD
SCHEMBL9560358 0.89 CETP (0.43) CETPFFAR1MRGPRX4PPARDFFAR4
SCHEMBL9570790 0.88 EGFR (0.36) FFAR1MRGPRX4EGFRPPARDPPARA
SCHEMBL9570718 0.87 CETP (0.40) CETPFFAR1PPARATACR1
SCHEMBL409247 0.87 FFAR1 (0.51) CETPFFAR1MRGPRX4FFAR4
SCHEMBL9561406 0.87 FFAR1 (0.51) CETPFFAR1MRGPRX4FFAR4
SCHEMBL9560714 0.86 ALDH1A1 (0.38) CETPFFAR1MRGPRX4EGFRPPARD
SCHEMBL9862593 0.84 FFAR1 (0.44) CETPFFAR1MRGPRX4PPARAFFAR4
SCHEMBL29370536 0.84 FFAR1 (0.44) CETPFFAR1MRGPRX4PPARAFFAR4
SCHEMBL118655 0.84 FFAR1 (0.44) CETPFFAR1MRGPRX4PPARAFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed