Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351076 | 0.89 | ALDH1A1 (0.48) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL744307 | 0.89 | ALDH1A1 (0.48) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL10745473 | 0.87 | ALDH1A1 (0.59) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL6949727 | 0.85 | KMT2A (0.49) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL29383650 | 0.85 | KMT2A (0.49) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL2636596 | 0.85 | KMT2A (0.49) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL8412555 | 0.85 | TDP1 (0.44) | MAPTALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL6956134 | 0.85 | TDP1 (0.53) | MAPTALDH1A1LMNAGAATDP1 | |
| SCHEMBL6956189 | 0.85 | TDP1 (0.53) | MAPTALDH1A1LMNAGAATDP1 | |
| SCHEMBL6949730 | 0.84 | MAPT (0.44) | MAPTALDH1A1LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550008-A2 | Use of N-acyl derivatives of aminoalcohols with polycarboxylic acids for the manufacture of a medicament for the treatment of pathologies relating to mast cells | LIFEGROUP S.p.A. (IT) | 1993-07-07 | — | — | EP | claimed |
| EP-0550008-A2 | Use of N-acyl derivatives of aminoalcohols with polycarboxylic acids for the manufacture of a medicament for the treatment of pathologies relating to mast cells | LIFEGROUP S.p.A. (IT) | 1993-07-07 | — | — | EP | disclosed |