SCHEMBL9570774

SCHEMBL9570774

Fc1ccc(COCC(c2ccc(Cl)cc2)C(F)(F)F)cc1Sc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.37
TACR1 P25103 11/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
CACNA1F O60840 1/20 0.34
CACNA1D Q01668 1/20 0.34
CACNA1S Q13698 1/20 0.34
CACNA1C Q13936 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
MAPK1 P28482 1/20 0.31
MLNR O43193 1/20 0.31
NR1I2 O75469 1/20 0.31
PGR P06401 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADRA2B P18089 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570722 0.88 FFAR1 (0.36) TACR1L3MBTL1CACNA1FCACNA1DCACNA1S
SCHEMBL9570839 0.80 TACR1 (0.39) TACR1CACNA1FCACNA1DCACNA1SCACNA1C
SCHEMBL9561512 0.79 TACR1 (0.36) TACR1L3MBTL1CACNA1FCACNA1DCACNA1S
SCHEMBL9570586 0.79 FFAR1 (0.34) LMNASMN1; SMN2
SCHEMBL9560487 0.75 PPARG (0.47) TACR1LMNA
SCHEMBL9570621 0.74 PPARG (0.33) KMT2AESR1ESR2SLC6A4KCNH2
SCHEMBL9570700 0.74 PPARG (0.33) KMT2AESR1ESR2SLC6A4KCNH2
SCHEMBL9560890 0.72 CETP (0.44) TACR1LMNA
SCHEMBL9570632 0.72 DUT (0.35) TACR1CACNA1FCACNA1DCACNA1SCACNA1C
SCHEMBL9570690 0.72 SLC6A4 (0.41) TACR1CACNA1FCACNA1DCACNA1SCACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed