SCHEMBL9570783

SCHEMBL9570783

CCOc1ccc(C(COCc2ccc(F)c(Oc3ccc(F)cc3)c2)C(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CACNA1C Q13936 1/20 0.42
KMT2A Q03164 2/20 0.38
MAPT P10636 4/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
LMNA P02545 2/20 0.37
ATM Q13315 1/20 0.37
MEN1 O00255 1/20 0.36
FFAR1 O14842 3/20 0.36
TDP1 Q9NUW8 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
POLB P06746 1/20 0.34
SCN8A Q9UQD0 1/20 0.33
SCN10A Q9Y5Y9 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PLA2G1B P04054 1/20 0.33
GAA P10253 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862416 0.93 MAPT (0.40) CACNA1CKMT2AMAPTL3MBTL1LMNA
SCHEMBL409992 0.93 LTA4H (0.41) CACNA1CKMT2AMAPTL3MBTL1LMNA
SCHEMBL9560849 0.93 MAPT (0.40) CACNA1CKMT2AMAPTL3MBTL1LMNA
SCHEMBL9570596 0.93 CACNA1C (0.37) CACNA1CMAPTL3MBTL1LMNAATM
SCHEMBL9570736 0.93 CACNA1C (0.37) CACNA1CKMT2AMAPTL3MBTL1LMNA
SCHEMBL9561457 0.92 CACNA1C (0.36) CACNA1CKMT2AMAPTL3MBTL1LMNA
SCHEMBL9570784 0.92 L3MBTL1 (0.37) CACNA1CMAPTL3MBTL1LMNAATM
SCHEMBL9570581 0.92 MAPT (0.46) CACNA1CMAPTL3MBTL1LMNAATM
SCHEMBL9570657 0.91 CACNA1C (0.36) CACNA1CKMT2AMAPTL3MBTL1LMNA
SCHEMBL9570775 0.91 CACNA1C (0.40) CACNA1CKMT2AMAPTL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed