SCHEMBL9570845

SCHEMBL9570845

Cc1nc(NC(=O)C(C)C)sc1C(O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.57
GAA P10253 1/20 0.57
CYP2C9 P11712 1/20 0.57
RXFP1 Q9HBX9 1/20 0.57
XIAP P98170 1/20 0.43
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.42
CCNE1 P24864 1/20 0.41
CDK2 P24941 1/20 0.41
CDK5 Q00535 1/20 0.41
NPC1 O15118 6/20 0.40
RAB9A P51151 6/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570867 0.84 ALDH1A1 (0.47) CYP1A2GAACYP2C9RXFP1ALDH1A1
SCHEMBL9570921 0.81 ALDH1A1 (0.47) CYP1A2RXFP1ALDH1A1KDM4EHPGD
SCHEMBL19699520 0.77 RXFP1 (0.68) CYP1A2GAACYP2C9RXFP1XIAP
SCHEMBL25410224 0.76 RXFP1 (0.77) CYP1A2GAACYP2C9RXFP1XIAP
SCHEMBL25405454 0.71 GAA (0.72) CYP1A2GAACYP2C9RXFP1ALDH1A1
SCHEMBL19618661 0.70 CYP1A2 (0.57) CYP1A2GAACYP2C9RXFP1XIAP
SCHEMBL12894237 0.69 PIK3CG (0.54) CYP1A2GAACYP2C9RXFP1ALDH1A1
SCHEMBL24624425 0.68 RXFP1 (0.44) CYP1A2GAACYP2C9RXFP1XIAP
SCHEMBL24952924 0.68 XIAP (0.56) CYP1A2GAACYP2C9RXFP1XIAP
SCHEMBL17735695 0.66 CYP1A2 (0.56) CYP1A2GAACYP2C9RXFP1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0574118-A1 Polycyclic dyes ZENECA LIMITED (GB) 1993-12-15 EP disclosed