SCHEMBL9570867

SCHEMBL9570867

CC(=O)Nc1nc(C)c(C(O)C(=O)O)s1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
PIK3CG P48736 10/20 0.44
PIK3CD O00329 4/20 0.44
PIK3CA P42336 4/20 0.44
PIK3CB P42338 4/20 0.44
LCK P06239 1/20 0.43
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42
CYP2C9 P11712 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
DYRK1A Q13627 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570845 0.84 CYP1A2 (0.57) ALDH1A1HPGDCYP1A2GAACYP2C9
SCHEMBL9570921 0.83 ALDH1A1 (0.47) ALDH1A1HPGDCYP1A2RXFP1
SCHEMBL12894237 0.81 PIK3CG (0.54) ALDH1A1HPGDPIK3CGPIK3CDPIK3CA
SCHEMBL9570904 0.80 ALDH1A1 (0.40) ALDH1A1HPGDPIK3CGCYP1A2CYP2C9
SCHEMBL9570922 0.78 ALDH1A1 (0.39) ALDH1A1HPGDPIK3CGCYP1A2CYP2C9
SCHEMBL155142 0.73 RAB9A (0.57) ALDH1A1HPGDPIK3CGPIK3CDPIK3CA
SCHEMBL3585209 0.73 ALDH1A1 (0.64) ALDH1A1HPGDPIK3CGPIK3CDPIK3CA
SCHEMBL24599388 0.72 ALDH1A1 (0.48) ALDH1A1HPGDPIK3CGPIK3CDPIK3CA
SCHEMBL10963101 0.72 ALDH1A1 (0.45) ALDH1A1HPGDPIK3CGPIK3CDPIK3CA
SCHEMBL19725069 0.71 GAA (0.47) ALDH1A1HPGDPIK3CGPIK3CDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0574118-A1 Polycyclic dyes ZENECA LIMITED (GB) 1993-12-15 EP disclosed