Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 8/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570909 | 0.90 | MEN1 (0.35) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9570903 | 0.86 | KCNH2 (0.49) | MEN1KMT2AKCNH2POLBTOP2A | |
| SCHEMBL9570738 | 0.83 | MEN1 (0.42) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9570695 | 0.83 | ALDH1A1 (0.55) | MEN1KMT2AKCNH2POLBGSK3B | |
| SCHEMBL9570905 | 0.77 | KCNH2 (0.40) | MEN1KMT2AKCNH2POLBTOP2A | |
| SCHEMBL8982837 | 0.76 | MEN1 (0.56) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9570699 | 0.74 | ALDH1A1 (0.45) | MEN1KMT2AKCNH2POLBGSK3B | |
| SCHEMBL8852507 | 0.72 | MEN1 (0.59) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9570855 | 0.72 | MEN1 (0.51) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9570694 | 0.69 | ALDH1A1 (0.57) | MEN1KMT2AKCNH2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550903-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1993-07-14 | — | — | EP | disclosed |