SCHEMBL9570912

SCHEMBL9570912

C=CCOc1ccc(C(CO)C(F)(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CYP2D6 P10635 1/20 0.41
NPC1 O15118 4/20 0.39
RAB9A P51151 3/20 0.39
TP53 P04637 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 2/20 0.39
APOBEC3A P31941 1/20 0.39
CASP6 P55212 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
MAPT P10636 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9418032 0.82 CYP2D6 (0.46) CA12CA1CA2CA7CA9
SCHEMBL9551798 0.82 POLB (0.44) CA12CA1CA2CA7CA9
SCHEMBL9561666 0.78 NQO1 (0.50) MEN1KMT2AMAPTLMNAADRA2A
SCHEMBL9560409 0.78 NQO1 (0.50) MEN1KMT2AMAPTLMNAADRA2A
SCHEMBL10555386 0.78 NQO1 (0.50) MEN1KMT2AMAPTLMNAADRA2A
SCHEMBL9570785 0.77 ESR1 (0.46) CYP2D6TP53MEN1KMT2APOLB
SCHEMBL9570650 0.76 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL9570862 0.76 ALDH1A1 (0.41) ESR1ESR2ALDH1A1CHRNB2CHRNB4
SCHEMBL20391482 0.75 CYP2D6 (0.51) CA12CA1CA2CA7CA9
SCHEMBL9570861 0.75 LTA4H (0.46) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed