Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409235 | 0.84 | SRD5A1 (0.63) | SRD5A1SRD5A2 | |
| SCHEMBL7621779 | 0.84 | SRD5A1 (0.63) | SRD5A1SRD5A2 | |
| SCHEMBL14504017 | 0.83 | AR (0.58) | SRD5A2 | |
| SCHEMBL7616401 | 0.83 | AR (0.58) | SRD5A2 | |
| SCHEMBL8536963 | 0.79 | AKR1B10 (0.61) | — | |
| SCHEMBL7622722 | 0.78 | SRD5A2 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL13604056 | 0.77 | AR (0.58) | — | |
| SCHEMBL4180533 | 0.77 | AR (0.58) | — | |
| SCHEMBL14590313 | 0.77 | AR (0.58) | — | |
| SCHEMBL8795547 | 0.77 | SRD5A1 (0.56) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547690-A1 | Use of 17B-acyl-4-aza-5alpha-androst-1-en-3-ones for the preparation of a medicament for the prevention of prostatic carcinoma | MERCK & CO. INC. (US) | 1993-06-23 | — | — | EP | disclosed |
| EP-0414490-A2 | 17 Beta-acyl-4-aza-5 alpha-androst-1-ene-3-one as 5 alpha-reductase inhibitors | MERCK & CO. INC. (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0414491-A2 | 17 Beta-acyl-4-aza-5 alpha-androst-1-ene-3-ones as 5 alpha-reductase inhibitors | MERCK & CO. INC. (US) | 1991-02-27 | — | — | EP | disclosed |