Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570981 | 0.91 | POLB (0.31) | AGTR1AGTR2POLBL3MBTL1 | |
| SCHEMBL9570940 | 0.89 | AGTR1 (0.33) | AGTR1AGTR2POLBL3MBTL1 | |
| SCHEMBL9571074 | 0.87 | AGTR1 (0.33) | AGTR1AGTR2POLB | |
| SCHEMBL9233694 | 0.87 | SETDB1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL9570928 | 0.87 | AGTR1 (0.33) | AGTR1AGTR2POLBL3MBTL1 | |
| SCHEMBL9232782 | 0.84 | AGTR1 (0.30) | AGTR1AGTR2 | |
| SCHEMBL9571028 | 0.84 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL9571018 | 0.83 | AKT1 (0.36) | AGTR1AGTR2POLBL3MBTL1 | |
| SCHEMBL9570987 | 0.83 | AGTR1 (0.33) | AGTR1AGTR2 | |
| SCHEMBL9570970 | 0.81 | MEN1 (0.36) | AGTR1AGTR2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530702-A1 | 1,2-dihydro-2-oxopyridines as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-03-10 | — | — | EP | disclosed |