Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571028 | 0.88 | AGTR1 (0.34) | AGTR1AGTR2KDM4EALDH1A1GLA | |
| SCHEMBL9570928 | 0.87 | AGTR1 (0.33) | AGTR1AGTR2KDM4EALDH1A1GLA | |
| SCHEMBL9570940 | 0.86 | AGTR1 (0.33) | AGTR1AGTR2 | |
| SCHEMBL9571016 | 0.84 | KDM4E (0.34) | AGTR1AGTR2KDM4EALDH1A1GAA | |
| SCHEMBL9233694 | 0.84 | SETDB1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL9571074 | 0.84 | AGTR1 (0.33) | AGTR1AGTR2 | |
| SCHEMBL9570941 | 0.83 | AGTR1 (0.32) | AGTR1AGTR2 | |
| SCHEMBL9232782 | 0.83 | AGTR1 (0.30) | AGTR1AGTR2 | |
| SCHEMBL9570981 | 0.83 | POLB (0.31) | AGTR1AGTR2 | |
| SCHEMBL9571000 | 0.83 | AGTR1 (0.31) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530702-A1 | 1,2-dihydro-2-oxopyridines as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-03-10 | — | — | EP | disclosed |