Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31665546 | 0.80 | RAB9A (0.50) | ALDH1A1HPGDGPER1NPC1RAB9A | |
| SCHEMBL25143469 | 0.80 | RAB9A (0.50) | ALDH1A1HPGDGPER1NPC1RAB9A | |
| SCHEMBL25865063 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDDYRK1AADORA1NPC1 | |
| SCHEMBL155142 | 0.77 | RAB9A (0.57) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10719606 | 0.76 | DYRK1A (0.46) | ALDH1A1HPGDDYRK1AADORA1PIK3CG | |
| SCHEMBL12620553 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HPGDPI4KBPIK3CGPIK3CD | |
| SCHEMBL31665325 | 0.75 | RAB9A (0.59) | ALDH1A1HPGDGPER1NPC1RAB9A | |
| SCHEMBL9570904 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HPGDDYRK1AADORA1NPC1 | |
| SCHEMBL8124144 | 0.74 | MAPT (0.50) | ALDH1A1HPGDDYRK1AADORA1NPC1 | |
| SCHEMBL27099806 | 0.74 | DYRK1A (0.47) | ALDH1A1HPGDDYRK1AADORA1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574118-A1 | Polycyclic dyes | ZENECA LIMITED (GB) | 1993-12-15 | — | — | EP | disclosed |