Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31680271 | 0.84 | CA2 (0.56) | CA2CA1PTGS1PTGS2KDM1A | |
| SCHEMBL19567186 | 0.84 | PTGS1 (0.63) | CA2CA1PTGS1PTGS2KDM1A | |
| SCHEMBL21986566 | 0.84 | CA2 (0.56) | CA2CA1PTGS1PTGS2KDM1A | |
| SCHEMBL23514767 | 0.81 | CA2 (0.54) | CA2CA1PTGS1PTGS2KDM1A | |
| SCHEMBL20782066 | 0.81 | CA2 (0.54) | CA2CA1PTGS1PTGS2KDM1A | |
| SCHEMBL26022134 | 0.80 | CA2 (0.52) | CA2CA1PTGS1PTGS2KDM1A | |
| SCHEMBL9571488 | 0.80 | PTPN1 (0.58) | CA2CA1PTGS1PTGS2PTPN1 | |
| SCHEMBL29203533 | 0.78 | NR3C1 (0.59) | PTGS1HTR6NR3C1SMN1; SMN2CYP3A4 | |
| SCHEMBL30240812 | 0.78 | NR3C1 (0.59) | PTGS1HTR6NR3C1SMN1; SMN2CYP3A4 | |
| SCHEMBL7118308 | 0.78 | CA2 (0.61) | CA2CA1PTGS1PTGS2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546449-A2 | Benzofuranderivatives as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-06-16 | — | — | EP | disclosed |