Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 5/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572014 | 0.78 | PTPRC (0.78) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL31194258 | 0.78 | PTPRC (0.78) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL9572027 | 0.76 | PTPRC (0.48) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL9572025 | 0.76 | PTPRC (0.74) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL9572002 | 0.74 | CCR6 (0.47) | PTPRCGSK3BPRKCA | |
| SCHEMBL6237555 | 0.70 | PTPRC (1.00) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL9572021 | 0.69 | PTPRC (0.60) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL28505491 | 0.66 | CDK2 (0.60) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL9571997 | 0.66 | GSK3B (0.62) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL9572022 | 0.65 | GSK3B (0.64) | PTPRCCDK2CCNE2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |