Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 1.00 |
| ▸ | NAT1 | P18440 | 2/20 | 0.72 |
| ▸ | IGF1R | P08069 | 2/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.63 |
| ▸ | PIM1 | P11309 | 4/20 | 0.62 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.62 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | TDP2 | O95551 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | CASP9 | P55211 | 1/20 | 0.60 |
| ▸ | CASP6 | P55212 | 1/20 | 0.60 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15091770 | 1.00 | TTR (1.00) | TTRNAT1IGF1RGSK3BMEN1 | |
| SCHEMBL7464188 | 1.00 | TTR (1.00) | TTRNAT1IGF1RGSK3BMEN1 | |
| SCHEMBL9573270 | 0.84 | NAT1 (1.00) | TTRNAT1GSK3BMEN1KMT2A | |
| SCHEMBL8182122 | 0.84 | TTR (0.72) | TTRNAT1IGF1RGSK3BMEN1 | |
| SCHEMBL9573277 | 0.84 | NAT1 (1.00) | TTRNAT1GSK3BMEN1KMT2A | |
| SCHEMBL8182119 | 0.84 | TTR (0.72) | TTRNAT1IGF1RGSK3BMEN1 | |
| SCHEMBL1247451 | 0.81 | TTR (0.68) | TTRNAT1IGF1RGSK3BMEN1 | |
| SCHEMBL1247452 | 0.81 | TTR (0.68) | TTRNAT1IGF1RGSK3BMEN1 | |
| SCHEMBL6651682 | 0.81 | TTR (0.69) | TTRNAT1IGF1RGSK3BMEN1 | |
| SCHEMBL1249066 | 0.81 | TTR (0.69) | TTRIGF1RGSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | TTR 1695/4885NAT1 18/4885IGF1R 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.