Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 15/20 | 0.76 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.62 |
| ▸ | REN | P00797 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268894 | 1.00 | ACE (0.76) | ACEACE2RENLTA4H | |
| SCHEMBL6979828 | 1.00 | ACE (0.76) | ACEACE2RENLTA4H | |
| SCHEMBL5970431 | 1.00 | ACE (0.76) | ACEACE2RENLTA4H | |
| SCHEMBL9477156 | 1.00 | ACE (0.76) | ACEACE2RENLTA4H | |
| SCHEMBL8261181 | 1.00 | ACE (0.76) | ACEACE2RENLTA4H | |
| SCHEMBL8256761 | 0.94 | ACE (0.69) | ACEACE2RENLTA4H | |
| SCHEMBL8265844 | 0.92 | ACE (0.65) | ACEACE2REN | |
| SCHEMBL13533686 | 0.92 | ACE (0.65) | ACEACE2REN | |
| SCHEMBL8257846 | 0.92 | ACE (0.65) | ACEACE2REN | |
| SCHEMBL31197026 | 0.91 | ACE (0.67) | ACEACE2RENLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216125-A | Active ester used for production of acylated amino acids | SANSHIN KAGAKU KOGYO CO. LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5117031-A | ACTIVE ESTERS USED FOR PRODUCTION OF ESTERS OR AMIDES AND PROCESS FOR PRODUCING ESTERS OR AMIDES | SANSHIN KAGAKU KOGYO CO. LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0245662-B1 | P-HYDROXYPHENYLSULFONIUM SALTS AND THEIR USE IN THE PREPARATION OF ESTERS AND AMIDES | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0331988-A1 | Sulfonium compounds, as well as process for producing active esters and amides used for the production of amides | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4857656-A | Active esters used for production of esters or amides and process for producing esters or amides | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0245662-A1 | p-Hydroxyphenylsulfonium salts and their use in the preparation of esters and amides | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |