Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.65 |
| ▸ | REN | P00797 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.53 |
| ▸ | PREP | P48147 | 2/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8265844 | 1.00 | ACE (0.65) | ACERENOPRM1ACE2DPP4 | |
| SCHEMBL8257846 | 1.00 | ACE (0.65) | ACERENOPRM1ACE2DPP4 | |
| SCHEMBL8261181 | 0.92 | ACE (0.76) | ACERENACE2 | |
| SCHEMBL9574253 | 0.92 | ACE (0.76) | ACERENACE2 | |
| SCHEMBL8268894 | 0.92 | ACE (0.76) | ACERENACE2 | |
| SCHEMBL5970431 | 0.92 | ACE (0.76) | ACERENACE2 | |
| SCHEMBL6979828 | 0.92 | ACE (0.76) | ACERENACE2 | |
| SCHEMBL9477156 | 0.92 | ACE (0.76) | ACERENACE2 | |
| SCHEMBL20173744 | 0.89 | REN (0.58) | ACERENACE2 | |
| SCHEMBL18620591 | 0.89 | ACE (0.64) | ACERENACE2PREPCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022646-A1 | METHOD OF NEUTRALISING ORGANOBORONATES WITH ACIDS | TRIGEN LIMITED (GB) | 2010-01-28 | — | — | US | disclosed |
| US-20100022646-A1 | METHOD OF NEUTRALISING ORGANOBORONATES WITH ACIDS | TRIGEN LIMITED (GB) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022646-A1 | METHOD OF NEUTRALISING ORGANOBORONATES WITH ACIDS | LIPC, CYP8B1, SCD | ACE 1581/4885REN 2004/4885OPRM1 921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.