Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766081 | 0.88 | ADRB2 (0.38) | MAOBKDM4EMEN1KMT2AADRB2 | |
| SCHEMBL10465004 | 0.85 | BCHE (0.38) | MAOBKDM4EMEN1KMT2AADRB2 | |
| SCHEMBL10465045 | 0.84 | ADRB2 (0.42) | KDM4EALDH1A1MEN1KMT2AADRB2 | |
| SCHEMBL10463962 | 0.84 | MRGPRX4 (0.40) | MAOBKDM4EMEN1KMT2AADRB2 | |
| SCHEMBL5279071 | 0.83 | NR1H3 (0.37) | MAOBMEN1KMT2AADRB2ADRB1 | |
| SCHEMBL10465465 | 0.83 | BACE1 (0.39) | MAOBKMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL10464521 | 0.82 | ADRB2 (0.46) | KDM4EALDH1A1MEN1KMT2AADRB2 | |
| SCHEMBL10464981 | 0.82 | ADRB2 (0.43) | KDM4EALDH1A1MEN1KMT2AADRB2 | |
| SCHEMBL10465029 | 0.80 | ADRB2 (0.40) | KDM4EMEN1KMT2AADRB2TP53 | |
| SCHEMBL10478216 | 0.80 | NR1H3 (0.45) | MAOBL3MBTL1MEN1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243076-A | Adrenergic stimulant intermediates | GLAXO GROUP LTD. | 1993-09-07 | — | — | US | disclosed |
| US-5225445-A | Respiratory system disorders | GLAXO GROUP LTD. | 1993-07-06 | — | — | US | disclosed |
| US-5126375-A | Asthma, chronic bronchitis | GLAXO GROUP LTD. (GB) | 1992-06-30 | — | — | US | disclosed |
| US-5091422-A | Treating inflammatory or allergic skin disease, lowering gastric acidity | GLAXO GROUP LIMITED (GB) | 1992-02-25 | — | — | US | disclosed |
| US-4992474-A | Adrenergic stimulants | GLAXO GROUP LTD. (GB) | 1991-02-12 | — | — | US | disclosed |