Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196817 | 0.82 | KMT2A (0.42) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL260819 | 0.81 | MEN1 (0.47) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL31244372 | 0.81 | MEN1 (0.47) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL27702804 | 0.79 | MEN1 (0.46) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL9574478 | 0.79 | HTR6 (0.35) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL18494974 | 0.78 | CDK2 (0.40) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL1049737 | 0.78 | ALDH1A1 (0.41) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL10030668 | 0.78 | CYP1A2 (0.50) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL28592165 | 0.77 | CD44 (0.42) | KMT2AMEN1ESR1ESR2GAA | |
| Sulfuric Acid Dimethyl Ester SCHEMBL29076816 | 0.76 | MEN1 (0.44) | KMT2AMEN1ESR1ESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310944-B1 | BISOXETHYLSULFONYLMETHYL ANILINES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-13 | — | — | EP | disclosed |