Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778816 | 0.82 | CA1 (0.46) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6390788 | 0.79 | POLB (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8778749 | 0.78 | HSD17B10 (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5049913 | 0.75 | FPR2 (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL31171043 | 0.74 | HSD17B10 (0.47) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL750558 | 0.72 | CA2 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3252117 | 0.72 | CA1 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28657406 | 0.72 | PRSS1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3626579 | 0.72 | CA2 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6558824 | 0.72 | HSD17B10 (0.49) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310944-B1 | BISOXETHYLSULFONYLMETHYL ANILINES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-13 | — | — | EP | disclosed |