Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.64 |
| ▸ | PTPRC | P08575 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779167 | 0.91 | ALOX5 (0.59) | MRGPRX4MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1777985 | 0.89 | ALOX5 (0.60) | MRGPRX4MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10411878 | 0.87 | MRGPRX4 (0.77) | MRGPRX4MAOBCYSLTR1F2MAOA | |
| SCHEMBL31556116 | 0.84 | MAOB (0.58) | MRGPRX4MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28152490 | 0.84 | ALOX5 (0.67) | MRGPRX4MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10615958 | 0.84 | NPC1 (0.58) | MRGPRX4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL15549770 | 0.83 | NPC1 (0.54) | MRGPRX4MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15296747 | 0.83 | MAOB (0.74) | MRGPRX4PTPRCPTPN1MAOBNPC1 | |
| SCHEMBL9268448 | 0.83 | NPC1 (0.71) | MRGPRX4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6960292 | 0.82 | MRGPRX4 (0.72) | MRGPRX4MAOBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251795-B1 | NEW COMPOUNDS AND THEIR APPLICATION | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-4894359-A | BIS(PHENOXYMETHYL)BENZENE DERIVATIVES | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1990-01-16 | — | — | US | disclosed |
| US-4855482-A | New compounds and their application | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0251795-A2 | New compounds and their application | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-01-07 | — | — | EP | disclosed |