Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575245 | 0.88 | GAA (0.64) | GAAKMT2ALMNAESRRGNR5A2 | |
| SCHEMBL9575255 | 0.84 | GAA (0.59) | GAAKMT2ALMNANR5A2NR5A1 | |
| SCHEMBL9575286 | 0.84 | GAA (0.43) | GAAKMT2ALMNARAB9AMEN1 | |
| SCHEMBL11507342 | 0.81 | GAA (0.72) | GAAKMT2ALMNAESRRGNR5A2 | |
| SCHEMBL9575147 | 0.80 | GAA (0.62) | GAAKMT2ALMNAMEN1MAPT | |
| SCHEMBL8336553 | 0.77 | GAA (0.76) | GAAKMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL9575276 | 0.75 | GAA (0.45) | GAAKMT2APOLBLMNAMEN1 | |
| SCHEMBL8340801 | 0.74 | GAA (0.40) | GAAKMT2ALMNANPC1RAB9A | |
| SCHEMBL2069834 | 0.74 | MAPK1 (0.48) | GAAKMT2ALMNANPC1RAB9A | |
| SCHEMBL13507866 | 0.73 | KMT2A (0.64) | GAAKMT2ASMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303280-B1 | PHENOLIC ANTIOXIDANT HYDRAZIDES | ATOCHEM NORTH AMERICA, INC. (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0303280-A2 | Phenolic antioxidant hydrazides | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-15 | — | — | EP | disclosed |
| US-4801749-A | Phenolic antioxidant hydrazides | PENNWALT CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |