SCHEMBL8340801

SCHEMBL8340801

CCC(C)(C)c1cc(CCCN)cc(C(C)(C)CC)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.40
KMT2A Q03164 4/20 0.37
ALDH1A1 P00352 4/20 0.36
TSHR P16473 3/20 0.36
LMNA P02545 2/20 0.36
ESR1 P03372 1/20 0.36
CYP19A1 P11511 1/20 0.36
ESR2 Q92731 1/20 0.36
PTGS2 P35354 3/20 0.35
CYP3A4 P08684 3/20 0.35
MAPK1 P28482 3/20 0.35
NPSR1 Q6W5P4 3/20 0.35
MEN1 O00255 3/20 0.35
CYP1A2 P05177 2/20 0.35
BLM P54132 2/20 0.35
ATM Q13315 2/20 0.35
HIF1A Q16665 2/20 0.35
GMNN O75496 1/20 0.35
GABBR2 O75899 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575261 0.91 ESR1 (0.36) GAAKMT2AESR1CYP19A1ESR2
SCHEMBL8338486 0.89 GAA (0.41) GAAKMT2AALDH1A1TSHRLMNA
SCHEMBL2069834 0.86 MAPK1 (0.48) GAAKMT2AALDH1A1TSHRLMNA
SCHEMBL10547624 0.84 PTGS2 (0.53) GAAKMT2AALDH1A1TSHRLMNA
SCHEMBL2916130 0.84 TNKS2 (0.45) GAAKMT2AALDH1A1TSHRLMNA
SCHEMBL3678356 0.84 GAA (0.54) GAAKMT2AALDH1A1TSHRLMNA
Hydrochloric Acid SCHEMBL14603471 0.82 GAA (0.53) GAAKMT2AALDH1A1TSHRLMNA
SCHEMBL8339507 0.82 ALDH1A1 (0.40) GAAKMT2AALDH1A1TSHRLMNA
SCHEMBL11588699 0.81 GAA (0.39) GAAKMT2AALDH1A1TSHRLMNA
SCHEMBL2915436 0.80 ALDH1A1 (0.47) GAAKMT2AALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981065-A ELECTRICAL CONDUCTORS HAVING GREASE FILLED INTERSTICES THEREBETWEEN, EACH ELECTRICAL CONDUCTOR COVERING WITH POLYOLEFINS LAYER AND THE REACTION PRODUCT OF A HINDERED AMINE AMIC ACID HYDRAZIDE, A PHENOL OR AN AMINE HYDRAZIDE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-11-09 US disclosed
WO-1993024938-A1 TELEPHONE CABLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-12-09 WO disclosed
WO-1993024935-A1 TELEPHONE CABLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-12-09 WO disclosed
WO-1993024937-A1 TELEPHONE CABLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-12-09 WO disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed