Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656607 | 0.86 | KDM4E (0.37) | POLB | |
| SCHEMBL9575225 | 0.81 | HSD17B10 (0.41) | — | |
| SCHEMBL9575299 | 0.79 | SMN1; SMN2 (0.45) | POLB | |
| SCHEMBL9575667 | 0.78 | PDK1 (0.35) | GPR35 | |
| SCHEMBL9575524 | 0.78 | HPGD (0.33) | — | |
| SCHEMBL4641535 | 0.77 | POLB (0.40) | POLBGPR35NMT1 | |
| SCHEMBL9579561 | 0.76 | CA1 (0.33) | POLB | |
| SCHEMBL9575203 | 0.76 | — | — | |
| SCHEMBL4641540 | 0.73 | POLB (0.43) | POLBNMT1 | |
| SCHEMBL4644365 | 0.73 | POLB (0.38) | POLBGPR35NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266668-A | Substituted phenyl α-fluoroacrylates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| EP-0249867-B1 | SUBSTITUTED PHENYL ESTERS OF ALPHA-FLUOROACRYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0249867-A2 | Substituted phenyl esters of alpha-fluoroacrylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-23 | — | — | EP | disclosed |