SCHEMBL9575170

SCHEMBL9575170

C=C(F)C(=O)Oc1cccc(C(F)(F)F)c1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.49
ACR P10323 1/20 0.49
KDM4E B2RXH2 1/20 0.48
ATM Q13315 1/20 0.46
CES2 O00748 1/20 0.46
PPARG P37231 4/20 0.46
PPARA Q07869 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.45
MAOB P27338 1/20 0.43
AOC3 Q16853 1/20 0.43
MAPT P10636 2/20 0.43
FAAH O00519 1/20 0.43
LMNA P02545 1/20 0.43
NR4A2 P43354 1/20 0.42
TRPA1 O75762 1/20 0.41
TRPV1 Q8NER1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11860150 0.88 PRSS1 (0.55) PRSS1ACRKDM4EATMCES2
SCHEMBL12758749 0.86 PRSS1 (0.38) PRSS1ACRKDM4EATMCES2
SCHEMBL11344203 0.86 PRSS1 (0.48) PRSS1ACRKDM4EATMCES2
SCHEMBL15836532 0.86 ATM (0.48) PRSS1ACRKDM4EATMCES2
SCHEMBL18697300 0.83 PRSS1 (0.54) PRSS1ACRKDM4EATMCES2
SCHEMBL9575366 0.83 CES2 (0.44) CES2MAPTLMNA
SCHEMBL12469535 0.82 ATM (0.50) PRSS1ACRKDM4EATMCES2
SCHEMBL12636025 0.82 ATM (0.45) PRSS1ACRKDM4EATMCES2
SCHEMBL30116329 0.81 PRSS1 (0.55) PRSS1ACRKDM4EATMCES2
SCHEMBL11904756 0.81 PRSS1 (0.55) PRSS1ACRKDM4EATMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947792-B2 Production method of optical transmission medium FUJIFILM CORPORATION (JP) 2011-05-24 US disclosed
US-7646959-B2 Plastic optical fiber and manufacturing method thereof, and optical transmission system FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20090069514-A1 PRODUCTION METHOD OF OPTICAL TRANSMISSION MEDIUM FUJIFILM CORPORATION (JP) 2009-03-12 US disclosed
US-20090003834-A1 Plastic Optical Fiber and Manufacturing Method Thereof, and Optical Transmission System FUJIFILM CORPORATION (JP) 2009-01-01 US disclosed
US-5266668-A Substituted phenyl α-fluoroacrylates HOECHST AKTIENGESELLSCHAFT (DE) 1993-11-30 US disclosed
EP-0249867-B1 SUBSTITUTED PHENYL ESTERS OF ALPHA-FLUOROACRYLIC ACID HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-02 EP disclosed
EP-0249867-A2 Substituted phenyl esters of alpha-fluoroacrylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-23 EP disclosed
US-4259407-A POLYMER OF HALOGENATED ALKYL ALPHA-HALOGENATED ACRYLATE VLSI TECHNOLOGY RESEARCH ASSOCIATION (JP) 1981-03-31 US disclosed