Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | SOD1 | P00441 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | XPO1 | O14980 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004362 | 0.84 | ELANE (0.42) | CES2RXRARXRBRXRGMAPT | |
| SCHEMBL9575170 | 0.83 | PRSS1 (0.49) | CES2MAPTLMNA | |
| SCHEMBL9575659 | 0.81 | KIF11 (0.54) | CES2KIF11 | |
| SCHEMBL12758749 | 0.79 | PRSS1 (0.38) | CES2MAPTKIF11LMNA | |
| SCHEMBL15453834 | 0.78 | CES2 (0.52) | CES2RXRARXRBRXRGMAPT | |
| SCHEMBL9575250 | 0.77 | CES2 (0.36) | CES2RXRARXRBRXRGMAPT | |
| SCHEMBL7647561 | 0.76 | CES2 (0.50) | CES2RXRARXRBRXRGMAPT | |
| SCHEMBL29064876 | 0.76 | CES2 (0.45) | CES2RXRARXRBRXRGMAPT | |
| SCHEMBL15836526 | 0.75 | ELANE (0.39) | CES2RXRARXRBRXRGMAPT | |
| SCHEMBL9575148 | 0.75 | CYP4F2 (0.41) | CES2MAPTSOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266668-A | Substituted phenyl α-fluoroacrylates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| EP-0249867-B1 | SUBSTITUTED PHENYL ESTERS OF ALPHA-FLUOROACRYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |