Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521059 | 0.82 | ELANE (0.39) | KDM4EALDH1A1RAPGEF4MIFPOLB | |
| SCHEMBL9656607 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1POLBTDP1HTT | |
| SCHEMBL9575193 | 0.81 | — | — | |
| SCHEMBL18697273 | 0.79 | RAPGEF4 (0.37) | KDM4EALDH1A1RAPGEF4MIFPOLB | |
| SCHEMBL9575199 | 0.78 | MEN1 (0.41) | ALDH1A1TDP1HTTMAPTHSD17B10 | |
| SCHEMBL9575429 | 0.78 | CYP1A2 (0.37) | POLB | |
| SCHEMBL25823465 | 0.75 | CYP1A2 (0.35) | KDM4EALDH1A1MIFPOLBTDP1 | |
| SCHEMBL15509359 | 0.74 | RAPGEF4 (0.40) | KDM4EALDH1A1RAPGEF4MIFPOLB | |
| SCHEMBL9575374 | 0.74 | CA1 (0.38) | KDM4EALDH1A1HTTMAPT | |
| SCHEMBL16112941 | 0.74 | HPGD (0.38) | KDM4EALDH1A1RAPGEF4MIFPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266668-A | Substituted phenyl α-fluoroacrylates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| EP-0249867-B1 | SUBSTITUTED PHENYL ESTERS OF ALPHA-FLUOROACRYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |