SCHEMBL1521059

SCHEMBL1521059

C=C(C)C(=O)Oc1c(C)cc(C)cc1C

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.39
ALDH1A1 P00352 4/20 0.38
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
KDM4E B2RXH2 4/20 0.35
HTT P42858 2/20 0.35
TP53 P04637 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HSD17B10 Q99714 1/20 0.35
RAPGEF4 Q8WZA2 1/20 0.33
MIF P14174 1/20 0.33
LMNA P02545 2/20 0.32
POLB P06746 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16775425 0.90 PTPN1 (0.39) ELANEALDH1A1KMT2AATMKDM4E
SCHEMBL12253017 0.90 ELANE (0.33) ELANEALDH1A1KMT2AATMKDM4E
SCHEMBL17433296 0.88 ELANE (0.39) ELANEALDH1A1KMT2AATMKDM4E
SCHEMBL16639591 0.86 ELANE (0.45) ELANEALDH1A1KMT2AATMKDM4E
SCHEMBL18328824 0.86 CYP3A4 (0.38) ELANEALDH1A1KMT2AATMKDM4E
SCHEMBL24244636 0.85 ELANE (0.37) ELANEALDH1A1KMT2AATMKDM4E
SCHEMBL14173150 0.83 ELANE (0.36) ELANEALDH1A1KMT2AATMKDM4E
SCHEMBL25926083 0.83 ELANE (0.36) ELANEALDH1A1KMT2AATMKDM4E
SCHEMBL9575172 0.82 KDM4E (0.33) ALDH1A1KMT2AKDM4EHTTTP53
SCHEMBL11059027 0.82 GAA (0.37) ELANEALDH1A1KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2277496-B1 Dental material containing surface-modified fillers IVOCLAR VIVADENT AG (LI) 2016-03-30 EP claimed
US-7714034-B2 Photopolymerizable dental materials with bisacylphosphine oxides as initiators IVOCLAR VIVADENT AG (LI) 2010-05-11 US claimed
EP-1749513-B1 Photopolymerisable dental material with bisacylphosphine oxides as initiator IVOCLAR VIVADENT AG (LI) 2009-03-04 EP claimed
US-20070027229-A1 Photopolymerizable dental materials with bisacylphosphine oxides as initiators IVOCLAR VIVADENT AG (LI) 2007-02-01 US claimed
EP-1374829-B1 Dental material on the basis of acryloester phosphonic acid IVOCLAR VIVADENT AG (LI) 2005-11-02 EP claimed
US-6900251-B2 Dental materials based on acrylic-ester phosphonic acids IVOCLAR VIVADENT AG (LI) 2005-05-31 US claimed
US-20040077754-A1 Dental materials based on acrylic-ester phosphonic acids IVOCLAR VIVADENT AG (LI) 2004-04-22 US claimed
WO-2024150677-A1 ACTIVE-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION 富士フイルム株式会社 2024-07-18 WO disclosed
WO-2024150676-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION 富士フイルム株式会社 2024-07-18 WO disclosed
US-11827793-B2 Core-shell compound, photosensitive resin composition including the same, photosensitive resin layer, color filter and CMOS image sensor SAMSUNG SDI CO., LTD. (KR) 2023-11-28 US disclosed
US-11807716-B2 Oligomer (2,6-dimethylphenylene ether) together with fabrication method and cured product thereof CPC CORPORATION, TAIWAN (TW) 2023-11-07 US disclosed
US-11401287-B2 Long-wave absorbing photoinitiators IVOCLAR VIVADENT AG (LI) 2022-08-02 US disclosed
US-20220204775-A1 CORE-SHELL COMPOUND, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME, PHOTOSENSITIVE RESIN LAYER, COLOR FILTER AND CMOS IMAGE SENSOR SAMSUNG SDI CO., LTD. (KR) 2022-06-30 US disclosed
US-6900251-B2 Dental materials based on acrylic-ester phosphonic acids IVOCLAR VIVADENT AG (LI) 2005-05-31 US disclosed
US-20040077882-A1 Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials IVOCLAR VIVADENT AG (LI) 2004-04-22 US disclosed
US-20040077754-A1 Dental materials based on acrylic-ester phosphonic acids IVOCLAR VIVADENT AG (LI) 2004-04-22 US disclosed
EP-0489560-B1 Positive type photosensitive anionic electrodeposition coating resin composition HITACHI CHEMICAL CO LTD (JP) 1997-04-09 EP disclosed
US-5230984-A POSITIVE TYPE PHOTOSENSITIVE ANIONIC ELECTRODEPOSITION COATING RESIN COMPOSITION HITACHI CHEMICAL COMPANY, LTD. (JP) 1993-07-27 US disclosed
EP-0489560-A1 Positive type photosensitive anionic electrodeposition coating resin composition Hitachi Chemical Co., Ltd. (JP) 1992-06-10 EP disclosed
EP-0483717-A2 Polymer blends KURARAY CO., LTD. (JP) 1992-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11401287-B2 Long-wave absorbing photoinitiators CBR3, STRA6, NR2E3 ELANE 4320/4885ALDH1A1 1735/4885KMT2A 3260/4885
US-20040077882-A1 Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials SCO2, CBR1, CORO1C ELANE 4012/4885ALDH1A1 1884/4885KMT2A 4400/4885
US-20040077754-A1 Dental materials based on acrylic-ester phosphonic acids PHOSPHO1, RER1, PTGER1 ELANE 1375/4885ALDH1A1 804/4885KMT2A 3863/4885
US-20070027229-A1 Photopolymerizable dental materials with bisacylphosphine oxides as initiators PRXL2A, PGM2, PAM ELANE 4522/4885ALDH1A1 3487/4885KMT2A 3175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.