Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | JAK1 | P23458 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5410631 | 0.84 | SMN1; SMN2 (0.61) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2561428 | 0.83 | PTPN1 (0.65) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31379003 | 0.83 | PTPN1 (0.65) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30827199 | 0.81 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL149980 | 0.81 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29707545 | 0.81 | KDM4E (1.00) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL444059 | 0.81 | PTPN1 (0.67) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29145592 | 0.80 | SMN1; SMN2 (0.57) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1974978 | 0.80 | PTPN1 (0.71) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29489791 | 0.80 | PTPN1 (0.71) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5310506-A | — | — | None | — | — | JP | disclosed |
| US-8937091-B2 | Inhibitor of protein crosslinking and use of the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-01-20 | — | — | US | disclosed |
| US-8937091-B2 | Inhibitor of protein crosslinking and use of the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-01-20 | — | — | US | disclosed |
| US-8937091-B2 | Inhibitor of protein crosslinking and use of the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-01-20 | — | — | US | disclosed |
| US-20120277423-A1 | PROTEIN CROSSLINKING INHIBITOR AND USE OF THE SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY | 2012-11-01 | — | — | US | disclosed |
| US-20120277423-A1 | PROTEIN CROSSLINKING INHIBITOR AND USE OF THE SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY | 2012-11-01 | — | — | US | disclosed |
| US-20120277423-A1 | PROTEIN CROSSLINKING INHIBITOR AND USE OF THE SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY | 2012-11-01 | — | — | US | disclosed |
| JP-H05310506-A | INSECT-PROOFING AGENT AND INSECT-PROOF ARTICLE USING THE SAME | OSAKA KASEI KK | 1993-11-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277423-A1 | PROTEIN CROSSLINKING INHIBITOR AND USE OF THE SAME | ARGLU1, F12, CDKL1 | KDM4E 1192/4885HPGD 1499/4885ALDH1A1 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.