SCHEMBL9575215

SCHEMBL9575215

[CH2]CC(O)C(O)C(O)C(C)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6435291 0.91
SCHEMBL29186069 0.78 LMNA (0.30) LMNAL3MBTL1
SCHEMBL269953 0.78
SCHEMBL6702143 0.73 ALDH1A1 (0.50) LMNATDP1ALDH1A1
SCHEMBL600061 0.73 LMNA (0.69) LMNAL3MBTL1TDP1ALDH1A1
SCHEMBL2065096 0.73 LMNA (0.69) LMNAL3MBTL1TDP1ALDH1A1
SCHEMBL309466 0.73 LMNA (0.69) LMNAL3MBTL1TDP1ALDH1A1
SCHEMBL22128527 0.73 LMNA (0.69) LMNAL3MBTL1TDP1ALDH1A1
SCHEMBL13134752 0.73 LMNA (0.69) LMNAL3MBTL1TDP1ALDH1A1
SCHEMBL13296278 0.73 TSHR (0.44) LMNAL3MBTL1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5266673-A Compatibilizer for polymer blends and alloys MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-11-30 US disclosed
EP-0530442-A1 Process for producing a hydroxy-substituted poly (phenylene ether) resin MITSUBISHI CHEMICAL CORPORATION (JP) 1993-03-10 EP disclosed
US-RE31512-E SISOMICIN BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1984-01-31 US disclosed
EP-0019843-B1 SISOMICIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES BAYER AG (DE) 1982-09-29 EP disclosed
US-4312859-A ANTIBIOTICS, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-01-26 US disclosed
EP-0019843-A1 Sisomicin derivatives, process for their preparation and their use as medicines BAYER AG (DE) 1980-12-10 EP disclosed
US-4235888-A SISOMYCIN-TYPE ANTIBIOTICS BAYER AKTIENGESELLSCHAFT (DE) 1980-11-25 US disclosed
EP-0007996-A1 4,6-Di-0-(Aminoglycosyl)-1,3-diaminocyclitols, process for their preparation and pharmaceutical compositions containing them BAYER AG (DE) 1980-02-20 EP disclosed