SCHEMBL9575252

SCHEMBL9575252

CC(C)(C)c1cc(NC(=O)CCCCCCCCC(=O)NN)cc(C(C)(C)C)c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.65
ALDH1A1 P00352 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
KMT2A Q03164 2/20 0.47
HDAC3 O15379 4/20 0.43
HDAC1 Q13547 4/20 0.43
HDAC2 Q92769 4/20 0.43
HDAC10 Q969S8 4/20 0.43
HDAC11 Q96DB2 4/20 0.43
HDAC8 Q9BY41 4/20 0.43
HDAC6 Q9UBN7 4/20 0.43
HDAC4 P56524 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC9 Q9UKV0 2/20 0.43
HDAC5 Q9UQL6 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NCOR2 Q9Y618 2/20 0.39
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9743116 0.99 GAA (0.67) GAAALDH1A1TDP1KMT2AHDAC3
SCHEMBL9575165 0.93 GAA (0.70) GAAALDH1A1TDP1KMT2AL3MBTL1
SCHEMBL1410855 0.93 GAA (0.62) GAAALDH1A1TDP1KMT2AHDAC3
SCHEMBL10621247 0.87 GAA (0.55) GAAALDH1A1TDP1KMT2AHDAC3
SCHEMBL9366018 0.87 GAA (0.55) GAAALDH1A1TDP1KMT2AHDAC3
SCHEMBL10869776 0.84 GAA (0.53) GAAALDH1A1TDP1KMT2AHDAC3
SCHEMBL9595945 0.84 GAA (0.55) GAAALDH1A1TDP1KMT2AHDAC3
SCHEMBL9595268 0.82 GAA (0.57) GAAALDH1A1TDP1KMT2AHDAC3
SCHEMBL29282569 0.80 ALDH1A1 (0.62) GAAALDH1A1TDP1KMT2AMEN1
SCHEMBL9362445 0.80 GAA (0.47) GAAALDH1A1TDP1KMT2AHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303280-B1 PHENOLIC ANTIOXIDANT HYDRAZIDES ATOCHEM NORTH AMERICA, INC. (US) 1993-03-24 EP disclosed
US-5100940-A Heat and oxidation resistance ATOCHEM NORTH AMERICA, INC. (US) 1992-03-31 US disclosed
US-5068356-A HINDERED PHENOLIC N-(AMIDO)IMIDES ATOCHEM NORTH AMERICA, INC. (US) 1991-11-26 US disclosed
EP-0443540-A1 Hindered phenolic N-(amido)-imides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-08-28 EP disclosed
EP-0303280-A2 Phenolic antioxidant hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed
US-4801749-A Phenolic antioxidant hydrazides PENNWALT CORPORATION (US) 1989-01-31 US disclosed