SCHEMBL9366018

SCHEMBL9366018

CCCCCCCCCCCCCCCCCC(=O)Nc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.55
ALDH1A1 P00352 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
KMT2A Q03164 1/20 0.51
PSMB11 A5LHX3 1/20 0.50
PSMA7 O14818 1/20 0.50
PSMB1 P20618 1/20 0.50
PSMA1 P25786 1/20 0.50
PSMA2 P25787 1/20 0.50
PSMA3 P25788 1/20 0.50
PSMA4 P25789 1/20 0.50
PSMB8 P28062 1/20 0.50
PSMB9 P28065 1/20 0.50
PSMA5 P28066 1/20 0.50
PSMB4 P28070 1/20 0.50
PSMB6 P28072 1/20 0.50
PSMB5 P28074 1/20 0.50
PSMB10 P40306 1/20 0.50
PSMB3 P49720 1/20 0.50
PSMB2 P49721 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10621247 1.00 GAA (0.55) GAAALDH1A1TDP1KMT2APSMB11
SCHEMBL1410855 0.94 GAA (0.62) GAAALDH1A1TDP1KMT2ALMNA
SCHEMBL9362445 0.92 GAA (0.47) GAAALDH1A1TDP1KMT2APSMB11
SCHEMBL29282569 0.88 ALDH1A1 (0.62) GAAALDH1A1TDP1KMT2ALMNA
SCHEMBL9575252 0.87 GAA (0.65) GAAALDH1A1TDP1KMT2AHDAC8
SCHEMBL10869776 0.86 GAA (0.53) GAAALDH1A1TDP1KMT2ALMNA
SCHEMBL9595945 0.85 GAA (0.55) GAAALDH1A1TDP1KMT2ACYP1A2
SCHEMBL9743116 0.85 GAA (0.67) GAAALDH1A1TDP1KMT2ALMNA
SCHEMBL10625507 0.85 ALDH1A1 (0.57) ALDH1A1PSMB11PSMA7PSMB1PSMA1
SCHEMBL10620466 0.85 ALDH1A1 (0.57) ALDH1A1PSMB11PSMA7PSMB1PSMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4775710-A ETHYLENE-ALPHA-OLEFIN COPOLYMERS; HEAT, DISCOLORATION AND OXIDATION RESISTANT MALLINCKRODT, INC. (US) 1988-10-04 US claimed
US-4722956-A HEAT AND OXIDATION RESISTANCE MALLINCKRODT, INC. (US) 1988-02-02 US claimed
US-12544338-B2 Solid or semisolid lipid based dosage form stabilization through curing and addition of low HLB surfactant(s) R.P. SCHERER TECHNOLOGIES, LLC (US) 2026-02-10 US disclosed
EP-0374048-B1 4-Aminophenol derivatives and processes for preparing the same TANABE SEIYAKU CO (JP) 1994-08-17 EP disclosed
US-5047555-A Antiallergens, Antiinflammatory Agents TANABE SEIYAKU CO., LTD. (JP) 1991-09-10 US disclosed
US-4990671-A Method for making aminophenols and their amide derivatives MALLINCKRODT, INC. (US) 1991-02-05 US disclosed
EP-0374048-A1 4-Aminophenol derivatives and processes for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1990-06-20 EP disclosed
US-4775710-A ETHYLENE-ALPHA-OLEFIN COPOLYMERS; HEAT, DISCOLORATION AND OXIDATION RESISTANT MALLINCKRODT, INC. (US) 1988-10-04 US disclosed
US-4775710-A ETHYLENE-ALPHA-OLEFIN COPOLYMERS; HEAT, DISCOLORATION AND OXIDATION RESISTANT MALLINCKRODT, INC. (US) 1988-10-04 US disclosed
US-4722956-A HEAT AND OXIDATION RESISTANCE MALLINCKRODT, INC. (US) 1988-02-02 US disclosed
US-4722956-A HEAT AND OXIDATION RESISTANCE MALLINCKRODT, INC. (US) 1988-02-02 US disclosed
US-3957905-A HALOGENATED BISPHENYL COMPOUND, ANTIMONY COMPOUND TOYO BOSEKI KABUSHIKI KAISHA (JA) 1976-05-18 US disclosed
US-3956427-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3956298-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3948854-A Salicylic acid hydrazide stabilizers for polymers CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3948852-A Nickel stabilisers for synthetic polymers CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3943106-A POLYESTERS AND POLYAMIDS FROM HYDROXYBENZYLMALONIC ACID DERIVATIVES; STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3940363-A POLYMERS SANKYO COMPANY LIMITED (JA) 1976-02-24 US disclosed
US-3939175-A STABILIZER CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544338-B2 Solid or semisolid lipid based dosage form stabilization through curing and addition of low HLB surfactant(s) LIPA, MGLL, LIPG GAA 3824/4885ALDH1A1 4526/4885TDP1 3873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.