Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.62 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26259612 | 0.81 | IMPDH2 (0.64) | IMPDH2IMPDH1KDM4EALDH1A1USP2 | |
| SCHEMBL16428549 | 0.80 | POLB (0.49) | IMPDH2IMPDH1KDM4EALDH1A1USP2 | |
| SCHEMBL2987592 | 0.80 | IMPDH2 (0.79) | IMPDH2IMPDH1KDM4EALDH1A1USP2 | |
| SCHEMBL9806325 | 0.80 | IMPDH2 (0.62) | IMPDH2IMPDH1KDM4EALDH1A1USP2 | |
| SCHEMBL17086891 | 0.78 | CYP19A1 (0.45) | ALDH1A1ACHECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9806302 | 0.77 | IMPDH2 (0.54) | IMPDH2IMPDH1KDM4EALDH1A1USP2 | |
| SCHEMBL589078 | 0.77 | IMPDH2 (1.00) | IMPDH2IMPDH1KDM4EALDH1A1USP2 | |
| SCHEMBL9575279 | 0.76 | IMPDH2 (0.57) | IMPDH2IMPDH1KDM4EALDH1A1USP2 | |
| SCHEMBL3948263 | 0.75 | IMPDH2 (0.44) | IMPDH2IMPDH1KDM4EALDH1A1USP2 | |
| SCHEMBL38659237 | 0.75 | CYP19A1 (0.44) | ALDH1A1ACHECYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281315-B1 | (TRIFLUOROMETHYL) NAPHTHALENE RECOVERY PROCESS | ETHYL CORPORATION (US) | 1993-06-23 | — | — | EP | claimed |
| EP-0199646-B1 | PROCESS FOR PREPARING 6-ALKOXY-5-TRIFLUOROMETHYL-1-NAPHTOIC ACIDS AND NOVEL 1-CYANO-NAPHTALENE INTERMEDIATES | ETHYL CORPORATION (US) | 1991-09-11 | — | — | EP | claimed |
| US-4824989-A | TRIFLUOROMETHYLNAPHTHALENE FROM HALONAPHTHALENE AND TRIFLUOROACETATE | ETHYL CORPORATION (US) | 1989-04-25 | — | — | US | claimed |
| US-4824988-A | Process for recovering cuprous iodide catalyst used in synthesis of (trifluoromethyl)napthalenes | ETHYL CORPORATION (US) | 1989-04-25 | — | — | US | claimed |
| US-4822904-A | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1989-04-18 | — | — | US | claimed |
| US-4785131-A | Substituted cyanonaphthalene process | ETHYL CORPORATION (US) | 1988-11-15 | — | — | US | claimed |
| EP-0281315-A2 | (Trifluoromethyl) naphthalene recovery process | ETHYL CORPORATION (US) | 1988-09-07 | — | — | EP | claimed |
| EP-0199646-A2 | Process for preparing 6-alkoxy-5-trifluoromethyl-1-naphtoic acids and novel 1-cyano-naphtalene intermediates | ETHYL CORPORATION (US) | 1986-10-29 | — | — | EP | claimed |
| US-4590010-A | Substituted naphthoic acid process | ETHYL CORPORATION (US) | 1986-05-20 | — | — | US | claimed |
| EP-0281315-B1 | (TRIFLUOROMETHYL) NAPHTHALENE RECOVERY PROCESS | ETHYL CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| EP-0199646-B1 | PROCESS FOR PREPARING 6-ALKOXY-5-TRIFLUOROMETHYL-1-NAPHTOIC ACIDS AND NOVEL 1-CYANO-NAPHTALENE INTERMEDIATES | ETHYL CORPORATION (US) | 1991-09-11 | — | — | EP | disclosed |
| EP-0307519-B1 | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1991-04-17 | — | — | EP | disclosed |
| EP-0245679-B1 | DEHALOGENATION PROCESS | ETHYL CORPORATION (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4889951-A | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0268662-A1 | HOMOGENEOUS COPOLYMERIZATION OF NON-POLAR MONOMERS WITH IONIC AMPHIPHILIC MONOMERS. | DOW CHEMICAL CO (US) | 1988-06-01 | — | — | EP | disclosed |
| WO-1987007621-A1 | HOMOGENEOUS COPOLYMERIZATION OF NON-POLAR MONOMERS WITH IONIC AMPHIPHILIC MONOMERS | THE DOW CHEMICAL COMPANY (US) | 1987-12-17 | — | — | WO | disclosed |
| EP-0245679-A2 | Dehalogenation process | ETHYL CORPORATION (US) | 1987-11-19 | — | — | EP | disclosed |
| US-4699993-A | Perfluoroalkylnaphthalene compounds | ETHYL CORPORATION (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0199646-A2 | Process for preparing 6-alkoxy-5-trifluoromethyl-1-naphtoic acids and novel 1-cyano-naphtalene intermediates | ETHYL CORPORATION (US) | 1986-10-29 | — | — | EP | disclosed |
| US-4590010-A | Substituted naphthoic acid process | ETHYL CORPORATION (US) | 1986-05-20 | — | — | US | disclosed |