Sugi Predict

Sugi Predict / Compounds / SCHEMBL9575285

SCHEMBL9575285

SCHEMBL9575285

CCCN(CCC)c1nc(NCCC2CC(C)(C)NC(C)(C)C2)nc(NCCC2CC(C)(C)NC(C)(C)C2)n1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ MAPT P10636 3/20 0.34
▸ TSHR P16473 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ CRHR1 P34998 2/20 0.32
▸ SLC29A1 Q99808 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575307 0.93 CRHR1 (0.34) SMN1; SMN2TSHRCRHR1SLC29A1
SCHEMBL11622058 0.92 TSHR (0.35) SMN1; SMN2TSHR
SCHEMBL9497036 0.91 SMN1; SMN2 (0.38) SMN1; SMN2MAPTTSHRLMNACRHR1
SCHEMBL9575542 0.90 SLC29A1 (0.33) SMN1; SMN2TSHRCRHR1SLC29A1
SCHEMBL9575473 0.90 CA1 (0.36) TSHR
SCHEMBL9575327 0.87 SMN1; SMN2 (0.36) SMN1; SMN2MAPTTSHRLMNACRHR1
SCHEMBL9575437 0.85 SLC29A1 (0.36) SMN1; SMN2CRHR1SLC29A1
SCHEMBL13606375 0.85 TSHR (0.42) TSHRLMNA
SCHEMBL9575499 0.84 TSHR (0.36) TSHR
SCHEMBL9575343 0.83 SLC29A1 (0.37) SMN1; SMN2CRHR1SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227640-B1 POLYOLEFINS STABILISED BY BIS-(POLYALKYLPIPERIDINYL-AMINO)-1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1993-05-26 — — EP claimed
EP-0227640-B1 POLYOLEFINS STABILISED BY BIS-(POLYALKYLPIPERIDINYL-AMINO)-1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1993-05-26 — — EP disclosed