SCHEMBL9575437

SCHEMBL9575437

CCCCN(CCCC)c1nc(NCCCCC2CC(C)(C)NC(C)(C)C2)nc(NCCCCC2CC(C)(C)NC(C)(C)C2)n1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 2/20 0.36
CRHR1 P34998 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KCNH3 Q9ULD8 2/20 0.33
KMT2A Q03164 1/20 0.33
DNM2 P50570 7/20 0.31
MERTK Q12866 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575343 0.95 SLC29A1 (0.37) SLC29A1CRHR1SMN1; SMN2KCNH3KMT2A
SCHEMBL9497036 0.94 SMN1; SMN2 (0.38) SLC29A1CRHR1SMN1; SMN2KCNH3KMT2A
SCHEMBL294894 0.93 SLC29A1 (0.32) SLC29A1
SCHEMBL9575307 0.93 CRHR1 (0.34) SLC29A1CRHR1SMN1; SMN2
SCHEMBL9575159 0.89 CA1 (0.34)
SCHEMBL9575542 0.88 SLC29A1 (0.33) SLC29A1CRHR1SMN1; SMN2KCNH3KMT2A
SCHEMBL9575468 0.88 CA1 (0.33) KMT2A
SCHEMBL11429671 0.86 TSHR (0.33) KMT2A
SCHEMBL9575357 0.85 CRHR1 (0.36) SLC29A1CRHR1SMN1; SMN2
SCHEMBL9575285 0.85 SMN1; SMN2 (0.40) SLC29A1CRHR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227640-B1 POLYOLEFINS STABILISED BY BIS-(POLYALKYLPIPERIDINYL-AMINO)-1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1993-05-26 EP claimed
EP-0227640-B1 POLYOLEFINS STABILISED BY BIS-(POLYALKYLPIPERIDINYL-AMINO)-1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1993-05-26 EP disclosed